LONDON (Reuters) – The race to build up new immunotherapy treatments against cancer has sparked an unparalleled explosion within the oncology drug pipeline, using more than 2,000 defense mechanisms-boosting agents now in development.
It makes sense a scramble for patients to sign-up in numerous studies, duplication of effort and also the likely ultimate failure of numerous projects, experts say.
Aiman Shalabi from the non-profit Cancer Research Institute stated on Thursday that the global analysis, the very first available, had found 940 immunotherapy drugs in clinical stage development, having a further 1,064 in the preclinical stage.
This season alone, 469 new studies were began, having a target enrolment of 52,539 patients, based on data presented by Shalabi in a European Society for Medical Oncology meeting in Geneva and printed within the Annals of Oncology.
“The field is extremely promising and can deliver many breakthroughs to alter the grade of proper care of many cancer types,” Shalabi and colleagues authored within the journal. “However, it’s also very crowded, fragmented and uncoordinated with significant duplication.”
Roche Leader Severin Schwan thinks the mass hurry in to the hot new field of immunotherapy can result in multiple disappointments.
Because the world’s greatest cancer drug company, the Swiss group expects to emerge among a number of winners but Schwan also sees many failures along with a wave of consolidation.
“I cannot imagine within my wildest dreams that many of these medicines will reach the marketplace and become competitive. You will see a massive drop-from each one of these numerous studies, meaning many people that invested in to these trials will forfeit money,” he stated inside a interview on Wednesday.
“I would anticipate seeing a couple of winners and lots of losers.”
Shalabi stated there must be to re-think of cancer development and research, having a concentrate on more collaboration between both companies and academia.
Reporting by Ben Hirschler, editing by David Evans